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crispr library designer  (Addgene inc)


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    Structured Review

    Addgene inc crispr library designer
    Crispr Library Designer, supplied by Addgene inc, used in various techniques. Bioz Stars score: 93/100, based on 13 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/crispr+library+designer/Mouse+CRISPR+Activation+Library+(SAM+-+3+plasmid+system)+(Pooled+Library+%231000000075)/pm41086252-227-20-33
    Average 93 stars, based on 13 article reviews
    crispr library designer - by Bioz Stars, 2026-09
    93/100 stars

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    Related Articles

    CRISPR:

    Article Title: Senataxin promotes recombination fidelity during antigen receptor gene diversification.
    Article Snippet: Antigen receptor diversity depends on the assembly of variable (V), diverse (D), and joining (J) exons in genes encoding immunoglobulins (Igs) and T cell receptors (TCRs).. During V(D)J recombination, DNA doublestrand breaks (DSBs) introduced by the RAG1/2 nuclease complex are repaired by the process of nonhomologous endjoining (NHEJ).. We hypothesized that functional redundancies between NHEJ and the chromatin DSB response, which depends on the kinase ATM, potentially masked the activity of additional factors that regulate V(D)J recombination.

    Clone Assay:

    Article Title: Senataxin promotes recombination fidelity during antigen receptor gene diversification.
    Article Snippet: Antigen receptor diversity depends on the assembly of variable (V), diverse (D), and joining (J) exons in genes encoding immunoglobulins (Igs) and T cell receptors (TCRs).. During V(D)J recombination, DNA doublestrand breaks (DSBs) introduced by the RAG1/2 nuclease complex are repaired by the process of nonhomologous endjoining (NHEJ).. We hypothesized that functional redundancies between NHEJ and the chromatin DSB response, which depends on the kinase ATM, potentially masked the activity of additional factors that regulate V(D)J recombination.



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